Synthesis of 2, 6-dihalo-DL-tyrosines

RA Pascal Jr, YCJ Chen

Index: Pascal, Robert A.; Chen, Y.-C. Jack Journal of Organic Chemistry, 1985 , vol. 50, # 3 p. 408 - 410

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Citation Number: 10

Abstract

As part of a program of research on the mechanisms of catalysis by a-keto acid dioxygenases, it has been necessary for us to synthesize a variety of unusual a-keto acids for use as alternate substrates or inhibitors of these enzymes. It is convenient to prepare these compounds by the action of commercially available D-and L-amino acid oxidases on the corresponding a-amino acids, l and since an enormous number of a-amino acids have ...