Synthesis

Solid-phase synthesis of pyrrolo [3, 4-b] pyridines and related pyridine-fused heterocycles

A Bhandari, B Li, MA Gallop

Index: Bhandari, Ashok; Li, Bei; Gallop, Mark A. Synthesis, 1999 , # 11 p. 1951 - 1960

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Citation Number: 17

Abstract

Abstract: Sequential Hantzsch condensation and cyclative cleavage reactions have been used to define a novel solid-phase route to pyrrolo [3, 4-b] pyridines and related pyridine- fused heterocycles. A combinatorial library of~ 5000 compounds prepared via this chemistry is described. Key words: solid-phase synthesis, cyclative cleavage, pyrrolo (3, 4-b] pyridine, combinatorial library

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