2-(Quinuclidin-3-yl) pyrido [4, 3-b] indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists

RD Clark, AB Miller, J Berger, DB Repke…

Index: Journal of Medicinal Chemistry, , vol. 36, # 18 p. 2645 - 2657

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Citation Number: 93

Abstract

... The 4,balkano-bridged pyrido[4,3-blindolones 14 and 15, pyrrolo[3,2-clpyridinone 17, tetrahydropyrrolo[3,2,1- ijl[1,6lnaphthyridinone 19, and the benzofurano- and 0 1993 American Chemical Society ... Page 4. 2648 Journal of Medicinal Chemistry, 1993, Vol. 36, No. 18 ...

Carboxylation of indoles and pyrroles with CO 2 in the presence of dialkylaluminum halides

[Nemoto, Koji; Onozawa, Satoru; Egusa, Naoki; Morohashi, Naoya; Hattori, Tetsutaro Tetrahedron Letters, 2009 , vol. 50, # 31 p. 4512 - 4514]

2-(Quinuclidin-3-yl) pyrido [4, 3-b] indol-1-ones and isoquinolin-1-ones. Potent conformationally restricted 5-HT3 receptor antagonists

Abstract

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