Organic process research & development

Novelties of solid-liquid phase transfer catalysed synthesis of α-isopropyl-p-chlorophenyl acetonitrile from p-chlorophenyl acetonitrile

GD Yadav, YB Jadhav

Index: Yadav, Ganapati D.; Jadhav, Yogeeta B. Organic Process Research and Development, 2003 , vol. 7, # 4 p. 588 - 598

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Citation Number: 16

Abstract

C-Alkylation is an important class of synthetic reaction employed in the fine chemical industry. Although a number of C-alkylation reactions are reported under liquid-liquid (LL) phase transfer catalysis (PTC) leading to intensification of reaction rates, there is a dearth of information on similar reactions under the solid-liquid (SL) PTC including kinetics and mechanism. SL PTC offers higher rates of reaction and better selectivities to the desired ...