Synthesis and thermotropic properties of macrocyclic lipids related to archaebacterial membranes

…, S Brocchini, HP Hopkins, D Hamilton

Index: Menger; Chen; Brocchini; Hopkins; Hamilton Journal of the American Chemical Society, 1993 , vol. 115, # 15 p. 6600 - 6608

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Citation Number: 107

Abstract

Abstract: Macrocyclic phospholipids containing 3244 ring atoms were synthesized by a route involving a high-temperature Glaser oxidation as the key step. These lipids are analogous to mammalian phospholipids except a single extra carboncarbon bond joins thechain termini. The new lipids offered, therefore, an opportunity to examine thermotropic properties of their membranes when the chains within a given molecule are unable to move independently ...

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