Bioorganic & medicinal chemistry letters

Diamine preparation for synthesis of a water soluble Ni (II) salen complex

JM Shearer, SE Rokita

Index: Shearer, Jason M.; Rokita, Steven E. Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 3 p. 501 - 504

Full Text: HTML

Citation Number: 17

Abstract

A reliable and efficient synthesis of NiNi (II) salen complex useful in probing nucleic acid structure is described and illustrates a general approach for constructing cis diamines suitable for assembly into N2O2 Schiff base complexes. Two equivalents of an aryllithium reacted with 1, 4-dimethylpiperazine-2, 3-dione to form the symmetric α-dione. This material was then converted to its dioxime and reduced by TiCl4/NaBH4 to yield the meso-diamine ...

Related Articles:

Ruthenium Catalyzed Oxidation of 1, 2??Diols to 1, 2??Diketones Using Bromamine??T as an Oxidizing Agent

[Jain, Suman L.; Sharma, Vishal B.; Sain, Bir Synthetic Communications, 2005 , vol. 35, # 3 p. 465 - 469]

An effective synthesis of N, N-dimethylamides from carboxylic acids and a new route from N, N-dimethylamides to 1, 2-diaryl-1, 2-diketones

[Kumagai, Takashi; Anki, Tomohiro; Ebi, Takahiro; Konishi, Akihito; Matsumoto, Kouzou; Kurata, Hiroyuki; Kubo, Takashi; Katsumoto, Kenta; Kitamura, Chitoshi; Kawase, Takeshi Tetrahedron, 2010 , vol. 66, # 46 p. 8968 - 8973]

More Articles...