Tetrahedron Letters

Direct transformation of aldehydes to nitriles using iodine in ammonia water

S Talukdar, JL Hsu, TC Chou, JM Fang

Index: Talukdar, Sanjay; Hsu, Jue-Liang; Chou, Tzu-Chi; Fang, Jim-Min Tetrahedron Letters, 2001 , vol. 42, # 6 p. 1103 - 1105

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Citation Number: 101

Abstract

Formation of nitriles from the corresponding aldehydes is an important functional group transformation. 1., , and Many methods involve the initial conversion of aldehydes to aldoximes, which are subjected to dehydration to give nitriles. 2., , , , , and Direct conversion of aldehydes into nitriles without isolation of nitrogen-containing intermediates has also been explored. 3., , , , , , , and In most cases, aromatic aldehydes are preferably converted to ...

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