Lewis acid catalyzed Nenitzescu indole synthesis

VS Velezheva, AG Kornienko, SV Topilin…

Index: Velezheva, Valeriya S.; Kornienko, Albert G.; Topilin, Sergey V.; Turashev, Ascar D.; Peregudov, Alexander S.; Brennan, Patrick J. Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 4 p. 873 - 879

Full Text: HTML

Citation Number: 18

Abstract

5-Hydroxyindoles are found in nature and display a wide variety of biological activities [1, 2]. A series of polysubstituted 5-hydroxyindole-based agents have been developed recently including the antiviral and immunomodulatory drug arbidol, ethyl 6-bromo-4- dimethylaminomethyl-5-hydroxy-1-methyl-2-phenylthio-methylindole-3-carboxylate hydrochloride [3](and its 4-substituted derivatives [4]), as well as compounds of potential ...