Organic letters

Highly efficient continuous flow reactions using singlet oxygen as a “green” reagent

F Lévesque, PH Seeberger

Index: Levesque, Francois; Seeberger, Peter H. Organic Letters, 2011 , vol. 13, # 19 p. 5008 - 5011

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Citation Number: 87

Abstract

Described is a new method for the efficient in situ production of singlet oxygen in a simple continuous flow photochemical reactor. The extremely large interfacial area generated by running the biphasic mixture in a narrow channel at a high flow rate ensures high throughput as well as fast and efficient oxidation of various alkenes, 1, 3-dienes, and thioethers on a preparative scale.

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