New Double-Chain and Aromatic (α-Hydroxyalkyl) phosphorus Amphiphiles

A Brun, G Etemad-Moghadam

Index: Brun, Alice; Etemad-Moghadam, Guita Synthesis, 2002 , # 10 p. 1385 - 1390

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Citation Number: 18

Abstract

Abstract New double-chain bis-(α-hydroxyalkyl) phosphinic acids 1 are synthesized from NaH 2 PO 2· H 2 O and aliphatic aldehydes. Direct and quantitative one-pot synthesis of new 4-alkoxybenzaldehydes 2 is realized from 1-bromoalkanes and 4- hydroxybenzaldehyde. Addition of NaH 2 PO 2· H 2 O to aldehydes 2 leads to the formation of the bis-adducts and also to the cleavage of the ether bond. New [α-hydroxy-(4- ...