Functional analogs of CC-1065 and the duocarmycins incorporating the 9a-(chloromethyl)-1, 2, 9, 9a-tetrahydrocyclopropa [c] benz [e] indol-4-one (C2BI) alkylation …

DL Boger, MSS Palanki

Index: Boger, Dale L.; Palanki, Moorthy S.S. Journal of the American Chemical Society, 1992 , vol. 114, # 24 p. 9318 - 9327

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Citation Number: 52

Abstract

Functional Analogs of CC-1065 and the Duocarmycins ... 1,2,9,9a-tetrahydrocyclopropa[ c]benz[ elindol-4-one ( C2BI) Alkylation Subunit: Synthesis and Preliminary DNA ... Dale L. Boger* and Moorthy SS Palanki Contribution from the Department of Chemistry, The Scripps Research Institute, 10666 North Torrey Pines Road, La Jolla, California 92037. Received May 21, 1992 ... Abstract: A concise and effective nine to ten step synthesis of ...

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