Semisynthetic analogues of ginsenosides, glycosides from ginseng

LN Atopkina, VA Denisenko, NI Uvarova…

Index: Atopkina, Lyubov N.; Denisenko, Vladimir A.; Uvarova, Nina I.; Elyakov, Georgi B. Carbohydrate Research, 1988 , vol. 177, p. 101 - 110

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Citation Number: 23

Abstract

Abstract Glycosylation of the dammar-24-ene-3, 12β, 20 (S)-triols with 2, 3, 4, 6-tetra-O- acetyl-α-d-glucopyranosyl bromide (A) in the presence of silver oxide in dichloro-methane gives a mixture of the acetylated 3-, 12-, 20-, 3, 12-di-, and 3, 20-di-O-β-d-glucopyranosyl derivatives in a total yield of 83–84.5%. Under similar conditions, the 3-O-acetyl derivatives of dammar-24-ene-3, 12β, 20 (S)-triols give a mixture of 12-and 20-O-β-d-glucopyranosyl ...