Synlett

Efficient syntheses of the polyene fragments present in amphidinols

…, S Reymond, T Kreuzer, F Colobert, P Jourdain…

Index: Cossy, Janine; Tsuchiya, Tomoki; Ferrie, Laurent; Reymond, Sebastien; Kreuzer, Thomas; Colobert, Francoise; Jourdain, Pierre; Marko, Istvan E. Synlett, 2007 , # 14 p. 2286 - 2288

Full Text: HTML

Citation Number: 7

Abstract

Abstract The C53-C67 and C53-C65 polyene fragments of amphidinols have been synthesized in an efficient and convergent fashion from sorbic acid in good overall yields (30- 31%) by employing a chemoselective cross-metathesis of a Weinreb amide and a Julia- Kocienski olefination as the key steps.