Reactions of ketene acetals 1611Part 15. V. Guay and P. Brassard, Tetrahedron, 1984, 40, 5039.. The regiospecific synthesis of partially methylated purpurins

B Simoneau, B Paul

Index: Simoneau, Bruno; Brassard, Paul Tetrahedron, 1986 , vol. 42, # 14 p. 3767 - 3774

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Citation Number: 36

Abstract

Two novel vinylketene acetals, 1, 4-dimethoxy-1, 3-bistrimethylsiloxybutadiene and 1, 3, 4- trimethoxy-1-trimethylsiloxybutadiene have been prepared in view of their eventual application to the synthesis of the antitumor antibiotic bikaverin. Use of the former in the elaboration of anthraquinones has shown that structures proposed for two natural products, purpurin 1-methyl ether. and 8-hydroxypurpurin 1-methyl ether are in fact those of ...