Design and synthesis of reboxetine analogs morpholine derivatives as selective norepinephrine reuptake inhibitors

W Xu, DL Gray, SA Glase, NS Barta

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 20 p. 5550 - 5553

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Citation Number: 22

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 1). A number of such compounds were synthesized using the described chemistry and several of these morpholine derivatives are potent and selective NRI's as demonstrated by the measured MAT binding affinities for representative ...

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