Synthesis and biological activity of new anti-inflammatory compounds containing the 1, 4-benzodioxine and/or pyrrole system

Y Harrak, G Rosell, G Daidone, S Plescia…

Index: Mauleon; Antunez; Rosell Farmaco, 1989 , vol. 44, # 11 p. 1109 - 1117

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Citation Number: 65

Abstract

A series of substituted derivatives containing the 1, 4-benzodioxine or pyrrole nucleus are described. All the newly synthesized compounds were examined for their in vitro and in vivo anti-inflammatory activity. Several derivatives, including (S)-2, 14 and 17, showed more anti-