Tetrahedron

Facile synthesis of 4, 5, 6a, 7-tetrahydrodibenzo [de, g] chromene heterocycles and their transformation to phenanthrene alkaloids

N Kapadia, W Harding

Index: Kapadia, Nirav; Harding, Wayne Tetrahedron, 2013 , vol. 69, # 42 p. 8914 - 8920

Full Text: HTML

Citation Number: 4

Abstract

Abstract Oxa-Pictet–Spengler cyclization and microwave-assisted C–H arylation have been implemented as key steps in the synthesis of new isochroman heterocycles containing a 4, 5, 6a, 7-tetrahydrodibenzo [de, g] chromene motif. These isochromans may be easily transformed to phenanthrene alkaloids via acidic cleavage of the isochroman ring and standard synthetic manipulations thereafter. The route described is attractive in that it ...

Related Articles:

Intramolecular homolytic substitution at the sulfur atom: an alternative way to generate phosphorus-and sulfur-centered radicals

[Carta, Paola; Puljic, Nicolas; Robert, Carine; Dhimane, Anne-Lise; Ollivier, Cyril; Fensterbank, Louis; Lacote, Emmanuel; Malacria, Max Tetrahedron, 2008 , vol. 64, # 52 p. 11865 - 11875]

Discovery of a new boron-containing antifungal agent, 5-fluoro-1, 3-dihydro-1-hydroxy-2, 1-benzoxaborole (AN2690), for the potential treatment of onychomycosis

[Journal of Medicinal Chemistry, , vol. 49, # 15 p. 4447 - 4450]

Esterification of aldehydes and alcohols with pyridinium hydrobromide perbromide in water

[Synlett, , # 15 p. 2739 - 2745]

Synthesis of biological markers in fossil fuels. 2. Synthesis and carbon-13 NMR studies of substituted indans and tetralins

[Journal of Organic Chemistry, , vol. 49, # 22 p. 4226 - 4237]

Synthesis of biological markers in fossil fuels. 2. Synthesis and carbon-13 NMR studies of substituted indans and tetralins

[Journal of Organic Chemistry, , vol. 49, # 22 p. 4226 - 4237]

More Articles...