Chemistry Letters

A convenient synthesis of γ-acyl-and related δ-lactones

M Kato, H Saito, A Yoshikoshi

Index: kato, Michiharu; Saito, Hiroaki; Yoshikoshi, Akira Chemistry Letters, 1984 , p. 213 - 216

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Citation Number: 10

Abstract

γ-Acyl-and related δ-lactones having no 6 substituents were synthesized in a sequence of reactions, 1, 4-conjugate additions of sulfurstabilized acetate anions to α, β-unsaturated ketones, followed by trapping of the resultant ketone enolates with formaldehyde, mild lactonization, and desulfurization.