Self??Assembled Pentamers and Hexamers Linked through Quadruple??Hydrogen??Bonded 2??Ureido??4 [1H]??Pyrimidinones

…, JJ González, M Segura, P Prados…

Index: Keizer, Henk M.; Gonzalez, Juan J.; Segura, Margarita; Prados, Pilar; Sijbesma, Rint P.; Meijer; De Mendoza, Javier Chemistry - A European Journal, 2005 , vol. 11, # 16 p. 4602 - 4608

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Citation Number: 44

Abstract

Abstract The preorganization of bifunctional 2-ureido-4-pyrimidinones mediated by either 1, 3-substituted adamantane or meta-substituted phenylene ring linkers leads to the preferred formation of stable pentameric (1) 5 and hexameric (2) 6 assemblies, respectively. Despite the high binding constant of the 2-ureido-4-pyrimidinone dimers and the highly preorganized structure of the monomer, the predominant formation of cycles (1) 5 and (2) ...

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