Total synthesis of leukotriene B4 [(+)-LTB4] and homo-LTB4 from D-mannitol

Y Le Merrer, C Gravier-Pelletier…

Index: Journal of Organic Chemistry, , vol. 54, # 10 p. 2409 - 2416

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Citation Number: 25

Abstract

... Chem., Vol. ... C l ( 3 0 mL), and then the temperature was allowed to warm to 20 "C. After ether extraction (2 x 100 mL), the combined organic layers were ... of the solvent gave a syrup (2.40 g), which was used without further purification: 'H NMRI5 (90 MHz) 6 1.30 (t, 6 H, J = 7.5, OEt ...

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