Organic letters

Electrophilic allylations and benzylations of indoles in neutral aqueous or alcoholic solutions

M Westermaier, H Mayr

Index: Westermaier, Martin; Mayr, Herbert Organic Letters, 2006 , vol. 8, # 21 p. 4791 - 4794

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Citation Number: 76

Abstract

Facile access to substituted indoles is of general interest because indoles are building blocks of many natural products and have applications as pharmaceuticals, as agrochemicals, and in materials science. 1,2 Among the numerous methods to synthesize substituted indoles, substitution reactions play an important role, among which Friedel−Crafts-type reactions are relatively rare. Although the BF 3 ·OEt 2 -induced prenylation of indole with prenyl pyrophosphate ...

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