Expedient solid-phase synthesis of fluorogenic protease substrates using the 7-amino-4-carbamoylmethylcoumarin (ACC) fluorophore

DJ Maly, F Leonetti, BJ Backes…

Index: Journal of Organic Chemistry, , vol. 67, # 3 p. 910 - 915

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Citation Number: 99

Abstract

... The Journal of Organic ... J. Org. ... the use of the in situ activating agent HATU (N-[(dimethylamino)- 1-H-1,2,3-triazolo-[4,5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide) in the presence of an equimolar amount of the hindered organic base 2,4,6 ...

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