Diversity synthesis using the complimentary reactivity of rhodium (II)-and palladium (II)-catalyzed reactions

A Ni, JE France, HML Davies

Index: Ni, Aiwu; France, Jessica E.; Davies, Huw M. L. Journal of Organic Chemistry, 2006 , vol. 71, # 15 p. 5594 - 5598

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Citation Number: 20

Abstract

Rhodium (II)-catalyzed reactions of aryldiazoacetates can be conducted in the presence of iodide, triflate, organoboron, and organostannane functionality, resulting in the formation of a variety of cyclopropanes or CH insertion products with high stereoselectivity. The combination of the rhodium (II)-catalyzed reaction with a subsequent palladium (II)-catalyzed Suzuki coupling offers a novel strategy for diversity synthesis.