The Ant??Pro Reverse??Turn Motif. Structural Features and Conformational Characteristics

…, RG Gonnade, RL Gawade, VG Puranik…

Index: Thorat, Vijaykumar H.; Ingole, Tukaram S.; Vijayadas, Kuruppanthara N.; Nair, Roshna V.; Kale, Sangram S.; Ramesh, Veera V.E.; Davis, Hilda C.; Prabhakaran, Panchami; Gonnade, Rajesh G.; Gawade, Rupesh L.; Puranik, Vedavati G.; Rajamohanan, Pattuparambil R.; Sanjayan, Gangadhar J. European Journal of Organic Chemistry, 2013 , # 17 p. 3529 - 3542

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Citation Number: 8

Abstract

Abstract This article details the characteristic conformational features of the Ant-Pro reverse turn―a folded pseudo β-turn motif that displays a closed nine-membered-ring hydrogen- bonded network involving just two amino acid residues, namely anthranilic acid (Ant; a constrained β-amino acid), and proline (Pro; a constrained α-amino acid). The results from the extensive investigation of ten crystal structures and their NMR conformations in the ...