Efficient reducing system based on iron for conversion of nitroarenes to anilines

ZP Xiao, YC Wang, GY Du, J Wu, T Luo…

Index: Xiao, Zhu-Ping; Wang, Ying-Chun; Du, Gao-Yu; Wu, Jun; Luo, Tao; Yi, Shou-Fu Synthetic Communications, 2010 , vol. 40, # 5 p. 661 - 665

Full Text: HTML

Citation Number: 10

Abstract

Reduction of nitroarenes with low solubility in EtOH–H2O to anilines easily occurs in a Fe– NH4Cl–acetone–H2O system, and treatment of the same nitroarenes with Fe–NH4Cl–EtOH– H2O hardly furnished the corresponding products. Under the reaction condition, the reducible or hydrolysable groups are not affected.