A practical and enantioselective synthesis of glycosphingolipids and related compounds. Total synthesis of globotriaosylceramide (Gb3)

…, T Caulfield, H Kataoka, T Kumazawa

Index: Nicolaou, K. C.; Caulfield, T.; Kataoka, H.; Kumazawa, T. Journal of the American Chemical Society, 1988 , vol. 110, # 23 p. 7910 - 7912

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Citation Number: 130

Abstract

Glycosphingolipids are a class of naturally occurring bioactive compounds usually embedded in the membrane of all animal cells and in some plant cells.'The clinically important blood group antigens2 and the immunologically relevant tumor-associated oligosaccharides3 are examples of glycosphingolipids. The" intelligent" roles attributed to these biomolecules include mediation of cell-cell recognition and communication, growth ...

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