Russian journal of applied chemistry

Synthesis of 6-methyluracil-5-sulfonyl chloride

IP Pogorelova, VD Orlov, AD Isak

Index: Pogorelova; Orlov; Isak Russian Journal of Applied Chemistry, 2006 , vol. 79, # 4 p. 631 - 633

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Citation Number: 1

Abstract

Abstract Sulfochlorination of 6-methyluracil with chlorosulfonic acid in the presence of thionyl chloride was studied. The lactam-lactim tautomerism of 6-methyluracil was considered. Ways to increase the yield of the sulfonyl chloride were suggested. The mechanism of the effect exerted by thionyl chloride additions was discussed.