Novel functionalized melamine-based nitroheterocycles: synthesis and activity against trypanosomatid parasites

A Baliani, V Peal, L Gros, R Brun, M Kaiser…

Index: Organic and Biomolecular Chemistry, , vol. 7, # 6 p. 1154 - 1166

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Citation Number: 17

Abstract

... Chemistry. The chemical start point was cyanuric chloride (1) which was converted to the key intermediate 2-amino-4,6-dichloro[1,3,5]triazine ... The solubility of hydrazone 5g in organic solvents was found to be dramatically improved compared to the hydrazone lead compound 5a ...