Il Farmaco

Antimicrobial activity of some N-alkyl and N-nitrobenzyl substituted halides of (E)-4′-hydroxy-3′-methoxystilbazoles-4

W Prukała, B Kędzia

Index: Prukala, Wieslaw; Kedzia, Bogdan Farmaco, 1999 , vol. 54, # 9 p. 584 - 587

Full Text: HTML

Citation Number: 11

Abstract

The synthesis of 11 new N-substituted derivatives of (E)-4′-hydroxy-3′- methoxystilbazoles-4 and their antimicrobial activity are reported. The relationships between structure and antibacterial activity are studied. In particular, compounds 5, 7 and 8 showed good antibacterial activity against Staphylococcusaureus, Streptococcus faecalis and Bacillus subtilis, while compound 6 did so against S. aureus and S. faecalis.