Tetrahedron Letters

N-Chlorosuccinimide as a versatile reagent for the sulfenylation of ketones: a facile synthesis of α-ketothioethers

JS Yadav, BVS Reddy, R Jain, G Baishya

Index: Yadav; Subba Reddy; Jain, Ruchi; Baishya, Gakul Tetrahedron Letters, 2008 , vol. 49, # 18 p. 3015 - 3018

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Citation Number: 30

Abstract

The sulfenylation of ketones having α-hydrogens has been achieved using N- chlorosuccinimide (NCS) under mild reaction conditions to produce α-ketothioethers in excellent yields with high selectivity. The use of NCS makes this method quite simple, convenient and practical.

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