European Journal of Organic Chemistry

Reaction of thiolesters with nitrogen ylides

S Voltrova, J Srogl

Index: Voltrova, Svatava; Srogl, Jiri European Journal of Organic Chemistry, 2008 , # 10 p. 1677 - 1679

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Citation Number: 3

Abstract

Abstract The pairing of unstabilized nitrogen ylides generated in situ with functionalized thiolesters under ambient conditions resulted in a new intramolecular carbon–carbon bond forming reaction. The scope of the reaction was illustrated with a series of substituted thiolester substrates. This reaction represents a new method for the synthesis of 2- substituted tetrahydrothienyl compounds through a unique 1, 2-thiolate shift. Whereas ...