Regiocontrolled Hydroarylation of (Trifluoromethyl) acetylenes in Superacids: Synthesis of CF3??Substituted 1, 1??Diarylethenes
…, VM Muzalevskiy, AV Vasilyev, GK Fukin…
Index: Alkhafaji, Haider M. H.; Ryabukhin, Dmitry S.; Muzalevskiy, Vasiliy M.; Vasilyev, Aleksander V.; Fukin, Georgy K.; Shastin, Alexey V.; Nenajdenko, Valentine G. European Journal of Organic Chemistry, 2013 , # 6 p. 1132 - 1143
Full Text: HTML
Citation Number: 6
Abstract
Abstract The reactions between aryl (trifluoromethyl)-substituted alkynes and arenes in triflic and fluorosulfonic acids were investigated. These reactions proceeded 100% regioselectively to give 1, 1-diaryl-2-trifluoromethylethenes in high yields. Depending on the workup conditions, 3, 3, 3-trifluoro-1, 1-diarylpropan-1-ol was also detected in the product mixture. The reaction mechanism was studied by both spectroscopic and theoretical ...
Related Articles:
[Dyker, Gerald; Heiermann, Joerg; Miura, Masahiro; Inoh, Jun-Ichi; Pivsa-Art, Sommai; Satoh, Tetsuya; Nomura, Masakatsu Chemistry - A European Journal, 2000 , vol. 6, # 18 p. 3426 - 3433]
[Shchukin; Vasil'Ev; Grinenko Russian Journal of Organic Chemistry, 2010 , vol. 46, # 1 p. 82 - 97]
[Tolbert,L.M.; Siddiqui,S. Journal of the American Chemical Society, 1984 , vol. 106, p. 5538]
[Shchukin; Vasil'Ev; Grinenko Russian Journal of Organic Chemistry, 2010 , vol. 46, # 1 p. 82 - 97]
[Jayamani, M.; Pillai, C. N. Synthetic Communications, 1985 , vol. 15, # 6 p. 535 - 542]