Investigating the anti-proliferative activity of styrylazanaphthalenes and azanaphthalenediones
A Mrozek-Wilczkiewicz, DS Kalinowski, R Musiol…
Index: Mrozek-Wilczkiewicz, Anna; Kalinowski, Danuta S.; Musiol, Robert; Finster, Jacek; Szurko, Agnieszka; Serafin, Katarzyna; Knas, Magdalena; Kamalapuram, Sishir K.; Kovacevic, Zaklina; Jampilek, Josef; Ratuszna, Alicja; Rzeszowska-Wolny, Joanna; Richardson, Des R.; Polanski, Jaroslaw Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 7 p. 2664 - 2671
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Citation Number: 29
Abstract
A group of styrylazanaphthalenes and azanaphthalenediones were synthesized and tested for their anti-proliferative activity. Most of the compounds were obtained with the use of microwave-assisted synthesis. The lipophilicity of the compounds was measured by RP- HPLC and their anti-proliferative activity was assayed against the human SK-N-MC neuroepithelioma and HCT116 human colon carcinoma cell lines. Active compounds ...
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