Tetrahedron

Syntheses of camalexin, indolopyridocoline and flavopereirine

A Fürstner, A Ernst

Index: Fuerstner, Alois; Ernst, Andreas Tetrahedron, 1995 , vol. 51, # 3 p. 773 - 786

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Citation Number: 65

Abstract

A short synthetic route to the phytoalexin camalexin 7 and a convergent approach to the alkaloids indolopyridocoline 8, 6, 7-dihydroflavopereirine 15 and flavopereirine 9 are presented. Starting from well accessible precursors, these total syntheses highlight the preparative potential of a new method for indole synthesis based on the formation of the C2 C3 bond by low-valent titanium induced reductive coupling of oxo-amides.

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