The Journal of Organic Chemistry

A Practical and Efficient Synthetic Route to Dihydropipercide and Pipercide1

LW Rotherham, JE Semple

Index: Rotherham, Lloyd W.; Edward Semple Journal of Organic Chemistry, 1998 , vol. 63, # 19 p. 6667 - 6672

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Citation Number: 12

Abstract

Dihydropipercide 1 and Pipercide 2 are examples of hydrophobic insecticidal isobutylamide derivatives isolated from Piper Nigrum L. which have received synthetic attention over the past decade. Novel structural features combining the N-isobutyldieneamide array, found in related natural products such as Pellitorine, with the 3, 4-methylenedioxyphenyl moiety, found in insecticide synergists including Piperonyl Butoxide and Sesamex, render these ...