Design and synthesis of antifungal benzoheterocyclic derivatives by scaffold hopping

C Sheng, X Che, W Wang, S Wang, Y Cao…

Index: European Journal of Medicinal Chemistry, , vol. 46, # 5 p. 1706 - 1712

Full Text: HTML

Citation Number: 35

Abstract

... European Journal of Medicinal Chemistry. ... rt, 10–30min 1 0–25%; f. 2-aminobenzenethiol, CH 2 Cl 2 , 0 °C∼ rt, 67.8%; g. 1-bromide alkylamine, K 2 CO 3 , MeOH, rt, 10–30min, 15–20%; h. formic anhydride, reflux, 5h, 68.2%; i. formamide, 150 °C, 7h, 75.5%; j. 1-bromoalkane ...

Related Articles:

Neuroleptic activity in 5-aryltetrahydro-. gamma.-carbolines

[Harbert, Charles A.; Plattner, Jacob J.; Welch, Willard M.; Weissman, Albert; Koe, B. Kenneth Journal of Medicinal Chemistry, 1980 , vol. 23, # 6 p. 635 - 643]

Synthesis and structure–activity relationships of γ-carboline derivatives as potent and selective cysLT 1 antagonists

[Bonjoch, Josep; Diaba, Faiza; Pages, Lluis; Perez, Daniel; Soca, Lidia; Miralpeix, Montserrat; Vilella, Dolors; Anton, Paquita; Puig, Carles Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 15 p. 4299 - 4302]

More Articles...