A new route to arglecin by metalation and cross coupling of pyrazines. Metalation of diazines. XII

…, D Dognon, C Harmoy, G Quéguiner

Index: Turck, A.; Ple, N.; Dognon, D.; Harmoy, C.; Queguiner, G. Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 6 p. 1449 - 1454

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Citation Number: 30

Abstract

Abstract The metalation of dihalogeno and halogenomethoxypyrazines was performed. The resulting pyrazines were submitted to a cross-coupling reaction with propargyl alcohol followed, after dehydration, by a catalytic reduction. This gives a new route to the synthesis of a key intermediate in the synthesis of arglecin.