Facile synthesis and anti-tumor cell activity of Se-containing nucleosides

…, J Sheng, RK Momin, Q Du, Z Huang

Index: Lin, Lina; Sheng, Jia; Momin, Razin K.; Du, Quan; Huang, Zhen Nucleosides, Nucleotides and Nucleic Acids, 2009 , vol. 28, # 1 p. 56 - 66

Full Text: HTML

Citation Number: 16

Abstract

Many organic compounds containing selenium have shown anticancer effects and some have been used in chemoprevention of cancers and other diseases. Though Se-containing amino acids are generally used for these purposes, the natural nucleosides may also be used as Se-carriers for these important applications. Therefore, we describe here the convenient synthesis of the new 3′-MeSe-thymidine nucleoside and the other uridine ...

Related Articles:

Functionalization of 2H-1, 2, 3-Triazole C-Nucleoside Template via N2 Selective Arylation

[McGuigan, Christopher; Hinsinger, Karen; Farleigh, Laura; Pathirana, Ranjith N.; Bugert, Joachim J. Journal of Medicinal Chemistry, 2013 , vol. 56, # 3 p. 1311 - 1322]

A new class of Spiegelmers containing 2′-fluoro-nucleotides

[Helmling; Moyroud; Schroeder; Roehl; Kleinjung; Stark; Bahrenberg; Gillen; Klussmann; Vonhoff Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 5-8 p. 1035 - 1038]

Functionalization of 2H-1, 2, 3-Triazole C-Nucleoside Template via N2 Selective Arylation

[McGuigan, Christopher; Hinsinger, Karen; Farleigh, Laura; Pathirana, Ranjith N.; Bugert, Joachim J. Journal of Medicinal Chemistry, 2013 , vol. 56, # 3 p. 1311 - 1322]

More Articles...