Synthesis of methyl (±)??2, 3??O??isopropylideneglycerate by electrochemical oxidation of (±)??1, 2??O??isopropylideneglycerol

KH Schwarz, K Kleiner, R Ludwig…

Index: Schwarz, Karl-Heinz; Kleiner, Katharina; Ludwig, Ralf; Schroetter, Eberhard; Schick, Hans Liebigs Annalen der Chemie, 1991 , # 5 p. 503 - 504

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Abstract

Abstract The anodic oxidation of (±)-1, 2-O-isopropylideneglycerol at a silver/silver oxide electrode with a controlled potential of+ 0.9 V vs. SCE in 2.5 N sodium hydroxide affords sodium (±)-2, 3-O-isopropylideneglycerate in a yield of 75%. Treatment of this salt with dimethyl sulfate and potassium carbonate in boiling acetone leads to methyl (±)-2, 3-O- isopropylideneglycerate in a yield of 81%.