Synthesis

An expeditious enantioselective synthesis of methyl trans-chrysanthemate

A Krief, W Dumont, D Baillieul

Index: Krief, Alain; Dumont, Willy; Baillieul, Diane Synthesis, 2002 , # 14 p. 2019 - 2022

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Citation Number: 6

Abstract

Abstract Methyl trans-chrysanthemate has been prepared in few steps from isopropylidenediphenylsulfurane and methyl (E)-3-(3, 3-dimethyloxiran-2-yl) prop-2-enoate. The latter was obtained from methyl 4-oxobutenoate or 3-methylbut-2-en-1-ol. The Sharpless catalytic epoxidation reaction allows an asymmetric version of this transformation.