Novel synthesis of the aldose reductase inhibitor sorbinil via amidoalkylation, intramolecular oxazolidin-5-one alkylation and chymotrypsin resolution

NL Dirlam, BS Moore, FJ Urban

Index: Journal of Organic Chemistry, , vol. 52, # 16 p. 3587 - 3591

Full Text: HTML

Citation Number: 41

Abstract

... 10, Applications of Biochemical Systems in Organic Chemistry; Jones, J. B., Sih, CJ, Perlman, D., Eds.; John Wiley and Sons: New York, 1977; Chapter 4. (21) (a) Cohen, SG; Schultz, R. M.; Weinstein, S. Y. J. Am. Chem. SOC. 1966, 88, 5315. ...