Tetrahedron letters

Synthesis of 3-methoxyquinolines via cyclization of 1-isocyano-2-(2-lithio-2-methoxyethenyl) benzenes

K Kobayashi, K Yoneda, T Mizumoto, H Umakoshi…

Index: Kobayashi, Kazuhiro; Yoneda, Keiichi; Mizumoto, Tatsuya; Umakoshi, Hironobu; Morikawa, Osamu; Konishi, Hisatoshi Tetrahedron Letters, 2003 , vol. 44, # 25 p. 4733 - 4736

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Citation Number: 26

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... 2-(2-Isocyanophenyl)acetaldehyde dimethyl acetals were treated with excess LDA to generate 1-isocyano-2-(2-lithio-2-methoxyethenyl)benzenes, which cyclized intramolecularly to afford 3-methoxyquinolines in good to excellent yields. ... 3-Methoxyquinolines were prepared ...

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