Reactions of some allylic and propargylic halides with nucleophiles analogous to those present in proteins and nucleic acids

JB Jones, DW Hysert

Index: Jones,J.B.; Hysert,D.W. Canadian Journal of Chemistry, 1971 , vol. 49, p. 325 - 332

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Citation Number: 22

Abstract

The relative alkylating capabilities of crotyl chloride, allyl bromide, and 1-bromo-2-butyne with respect to compounds containing thiol, imidazole, primary amino, and methylthio functions representative of those present in cysteine, histidine, lysine and methionine residues have been studied using 2-bromoacetophenone as the reference alkylating agent.