Pteridine Chemistry. III. 2-Amino-1 (and 3) 6, 7-trimethyl-4-pteridones and Some Related Compounds

WV Curran, RB Angier

Index: Curran; Angier Journal of the American Chemical Society, 1958 , vol. 80, p. 6095

Full Text: HTML

Citation Number: 13

Abstract

CH3) which was hydrolyzed easily to its% hydroxy analog in alkali, the 3-methyl derivative (117, R= CH3) when treated with hot I 11; sodium hydroxide readily underwent a rearrangement to give% methylamino-4-hydroxy-6, 7-dimethylpteridinc (VIII, R= CHs). Several similar type rearrangements have been reported in the literature involving other heterocyclic nuclei. For example, Elion'reported that treatment of the I-methyl derivative of ...