Efficient and selective synthesis of alkoxy substituted di (pyridin-2-yl) amines and N-arylpyridin-2-ylamines
IC Grig-Alexa, I Simionescu, OI Patriciu, S Massip…
Index: Grig-Alexa, Irina-Claudia; Simionescu, Iuliana; Patriciu, Oana-Irina; Massip, Stephane; Finaru, Adriana-Luminita; Jarry, Christian; Leger, Jean-Michel; Guillaumet, Gerald Tetrahedron Letters, 2012 , vol. 53, # 15 p. 1885 - 1888
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Citation Number: 3
Abstract
The formation of alkoxy substituted di (pyridin-2-yl) amines and N-arylpyridin-2-ylamines by nitro group reduction is described. Unexpected substitution of ortho with the amino at C-6 was observed during the reduction using SnCl2· 2H2O in different alcohols. The influence of the nature of the atom at the 3-and 5-positions of nitro-substituted di (pyridin-2-yl) amines and N-arylpyridin-2-ylamines was investigated.
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