Kinetic Resolution of Oxazinones: An Organocatalytic Approach to Enantiomerically Pure β??Amino Acids

…, F Cleemann, S Mukherjee

Index: Berkessel, Albrecht; Cleemann, Felix; Mukherjee, Santanu Angewandte Chemie - International Edition, 2005 , vol. 44, # 45 p. 7466 - 7469

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Citation Number: 82

Abstract

The development of new methods for the enantioselective synthesis of β-amino acids has been of considerable interest during the last years.[1–4] Owing to their unique pharmacological properties in the free form,[5] as cyclized β-lactams,[6] and as structural elements of naturally occurring compounds such as taxol [7] and the dolastatins,[8] there is a high demand in both academia and industry for enantiopure β-amino acids.[9] Besides ...

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