Ratiometric Fluorescent Signaling of Small Molecule, Environmentally Sensitive Dye Conjugates for Detecting Single??Base Mutations in DNA

C Wang, Y Sato, M Kudo, S Nishizawa…

Index: Wang, Chun-Xia; Sato, Yusuke; Kudo, Megumi; Nishizawa, Seiichi; Teramae, Norio Chemistry - A European Journal, 2012 , vol. 18, # 31 p. 9481 - 9484

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Citation Number: 3

Abstract

Since the report on Ca2+ indicators by Tsien and co-workers,[1] ratiometric fluorescent probes have come to be recognized as a promising tool for biosensing and bioimaging studies.[2] Significant efforts have been devoted to develop this class of probes for a wide range of analytes including metal ions,[3] inorganic and organic anions,[4] enzyme activities,[5] and nucleic acids.[6–8] A typical way to produce the ratiometric signal is by ...