Methylation of methyl α-d-hexopyranosides with diazo-methane in the presence of a small amount of water

Y Inoue, K Nagasawa

Index: Inoue, Yuko; Nagasawa, Kinzo Carbohydrate Research, 1987 , vol. 168, p. 181 - 190

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Citation Number: 2

Abstract

Abstract The long-time reduction of methyl α-d-gluco-, α-d-manno-, and α-d- galactopyranosides with excess diazomethane-diethyl ether at 25 in the presence of water gave all partially methylated methyl α-d-hexopyranosides which differ in number and position of methyl substitution. The presence of electrolytes, such as potassium or sodium phosphate, in the reaction medium enhanced the degree of methylation, resulting in ...