Antiinflammatory activity of some indan-1-carboxylic acids and related compounds

PF Juby, WR Goodwin, TW Hudyma…

Index: Juby,P.F. et al. Journal of Medicinal Chemistry, 1972 , vol. 15, p. 1297 - 1306

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Citation Number: 55

Abstract

A series of indan-1-carboxylic acids and derivatives was prepared as potential antiinflammatory agents. Many of the indan compounds showed potent antiinflammatory activity when tested orally in the rat. Structure-activity relationships are discussed, and a resemblance is noted between structural requirements for these antiinflammatory agents and for certain plant growth regulators.