Quadruply hydrogen-bonded heteroduplexes based on imide and urea units arrayed with ADDA/DAAD sequences

…, Y Ren, Y Wang, J Hu, T Ma, W Feng, L Yuan

Index: Li, Xianghui; Jia, Yiming; Ren, Yi; Wang, Youjia; Hu, Jinchuan; Ma, Teng; Feng, Wen; Yuan, Lihua Organic and Biomolecular Chemistry, 2013 , vol. 11, # 40 p. 6975 - 6983

Full Text: HTML

Citation Number: 5

Abstract

A new class of imide-and urea-based hetero-strands with a quadruple ADDA/DAAD hydrogen-bond array was designed and synthesized from easily accessible starting materials. The molecular recognition between the two different strands depends highly on the substituents and the linker between neighboring hydrogen-bonds, which results in the stability of these heteroduplexes varying from 103 to> 105 M− 1 in apolar solvents. In ...